Gastric Cancer
Adenocarcinoma that infiltrates the Cardias and the

Video Endoscopic Sequence 1 of 2.

Adenocarcinoma that infiltrates the Cardias and the Fundus.

This lady of 87 year-old, presented with dysphagia to solids and liquids, anorexia and anemia.

 

Adenocarcinoma that infiltrates the Cardias and the

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Endoscopic image of adenocarcinoma of the gastric fundus

Video Endoscopic Sequence 2 of 2.

Endoscopic image of adenocarcinoma of the gastric fundus

These image shows a ulcerated malignant tumor in the gastric fundus, (adenocarcinoma) retroflexed image.


Barrett Adenocarcinoma.

Video Endoscopic Sequence 1 of 4.

Barrett Adenocarcinoma.

This 85 year-old male, presented with dysphagia to solids and liquids, having a medical record to have been sufering long standing GERD.

 

 

Endoscopy of Barrett Adenocarcinoma

Video Endoscopic Sequence 2 of 4.

Endoscopy of Barrett Adenocarcinoma

 

 

 

 

 

Endoscopy of Barrett Adenocarcinoma

Video Endoscopic Sequence 3 of 4.

Endoscopy of Barrett Adenocarcinoma

The gastric cardias is infitrated by the neoplasia, retroflexed image.

 


Endoscopy of Barrett Adenocarcinoma

Video Endoscopic Sequence 4 of 4.

Endoscopy of Barrett Adenocarcinoma

Long Segment of Barrett´s Esophagus magnification endoscopy.





Endoscopic image of Barrett Adenocarcinoma

 ideo Endoscopic Sequence 1 of 20.

Endoscopic image of Barrett Adenocarcinoma

This 61 year-old male who four years previously, had made the diagnosis of Barrett's esophagus and has history of longstanding gastroesophageal reflux disease, to the point that the patient sleep almost sit, neither had received treatment with inhibitors of the proton pump inhibitors, or any endoscopic follow up.

At the time of this endoscopy, had 15 days suffering of dysphagia.

 

Endoscopic image of Barrett Adenocarcinoma





Barrett Adenocarcinoma

Video Endoscopic Sequence 2 of 20.

Image and Video Clip of Barrett Adenocarcinoma

In the image and the video clip shows a tongue of Barrett's esophagus of a long segment and the extensive malignant infiltration and a hiatus hernia

Over time the relative distribution of cancers of the proximal digestive tract has changed. Squamous cell carcinomas of the esophagus have become less common, while numbers of adenocarcinomas have greatly increased. This shift most likely reflects an increase in the incidence of gastroesophageal reflux. Moreover, there is a decline in the incidence of distal gastric cancer, which in turn may be related to Heliobacter pylori eradication.


Endoscopic image of Barrett Adenocarcinoma

Video Endoscopic Sequence 3 of 20.

In this video clip you can see, the extensive malignant infiltration, retroflexed image.

Simultaneously, there is a time trend toward a more proximal localization of gastric cancer. If the above-mentioned etiopathologic links are correct, this could indicate that the so-called cardia adenocarcinomas are not related to H pylori infection and that they may instead be related to gastroesophageal reflux and eventually may not be considered to be "gastric" cancers.

 



Endoscopic image of Barrett Adenocarcinoma

  Video Endoscopic Sequence 4 of 20.

Endoscopic image of Barrett Adenocarcinoma

In this video clip you can see, a tongue of the Barrett´s esophagus, which has been enhanced with acetic acid, and also shows the endoscopic biopsies.

The rapidly growing quantity of literature on this subject is, however, confounding. A major source of discordance would seem to be a Babylonian confusion of tongues concerning the terms cardia and cardiac carcinomas. Unfortunately, this confusion is also apparent in the classification systems available for staging of cancer, thus closing the "vicious" circle.


Barrett Adenocarcinoma

Video Endoscopic Sequence 5 of 20.

H&E

Gastric cardia adenocarcinoma, invasive mucosecretante,
intestinal type, moderately differentiated (grade 2).


Barrett Adenocarcinoma

Video Endoscopic Sequence 6 of 20.

 H&E

At the microscope is a mucus-secreting glandular neoplasia,

Barrett Adenocarcinoma

Video Endoscopic Sequence 7 of 20.

(Alcian blue positive).

 

Barrett Adenocarcinoma

Video Endoscopic Sequence 8 of 20.

Positive Citoqueratin +++

 



Barrett Adenocarcinoma

Video Endoscopic Sequence 9 of 20.

Positive Citoqueratin +++



V

Video Endoscopic Sequence 10 of 20.

Video clip of the surgical specimen, noting the esophagus and the gastric fundus.

 

Click on the image to download the video clip

 

Barrett Adenocarcinoma

Video Endoscopic Sequence 11 of 20.

Another video clip of the surgical specimen at the operating room.

 

 

 

 

 

 

Barrett Adenocarcinoma

Video Endoscopic Sequence 12 of 20.


Another video clip of part of the surgical procedure showing a clamp while cutting and stapler.

Barrett Adenocarcinoma

Video Endoscopic Sequence 13 of 20.

Macroscopic Specimen image of Barrett Adenocarcinoma

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Barrett Adenocarcinoma

Video Endoscopic Sequence 14 of 20.

Macroscopic Specimen image of Barrett Adenocarcinoma

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Barrett Adenocarcinoma

Video Endoscopic Sequence 15 of 20.

Macroscopic Specimen image of Barrett Adenocarcinoma

 

 

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Barrett Adenocarcinoma

Video Endoscopic Sequence 16 of 20.

Macroscopic Specimen image of Barrett Adenocarcinoma

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Barrett Adenocarcinoma

Video Endoscopic Sequence 17 of 20.

Macroscopic Specimen image of Barrett Adenocarcinoma

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Barrett Adenocarcinoma

Video Endoscopic Sequence 18 of 20.

Macroscopic Specimen image of Barrett Adenocarcinoma

The neoplasm arising in Barrett's epithelium.

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Barrett Adenocarcinoma

Video Endoscopic Sequence 19 of 20.

Macroscopic Specimen image of Barrett Adenocarcinoma

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Barrett Adenocarcinoma

Video Endoscopic Sequence 20 of 20.

Macroscopic Specimen image of Barrett Adenocarcinoma

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Synchronous Gastric Cancer

Video Endoscopic Sequence 1 of 4.

Synchronous Gastric Cancer

Double Cardia Cancer and Adenocarcinoma of the Antrum

This is a male 63 year-old male, presented with anorexia, dysphagia, and anemia. An upper endoscopic was performed finding two neoplasms. One in esophageal cardias spread to gastric cardia and one in the anterior wall of antrum

Second primary cancer influences the prognosis of gastric cancer patients, and because primary or secondary prevention is the best way to cure cancer, some investigators have focused on the characteristics of second primary cancers in gastric cancer patients. However, few studies have been performed in this regard, and most of these studies are limited to metachronous cancers or the treatment-related second primary malignancies of gastric cancer patients]. The detection of synchronous cancers gives us the opportunity to treat both cancers simultaneously using less invasive techniques and thus to benefi cially infl uence the prognosis and quality of life of these patients.The aim of this study was to find a means of identifying gastric cancer patients at risk of having a synchronous cancer.




 

Synchronous Gastric Cancer

Video Endoscopic Sequence 2 of 4.

Synchronous Gastric Adenocarcinoma

The gastric antrum is infiltrated with a second neoplasia.

Whilst synchronous adenocarcinoma of the stomach is well documented, metachronous primary disease is exceedingly rare.

Multiple synchronous gastric carcinomas are variously described in 1-3% of patients, and they occur typically in elderly men.


Synchronous Gastric Cancer

Video Endoscopic Sequence 3 of 4.

Endoscopic image of adenocarcinoma of the Gastric Fundus

The gastric cardia is infiltrated.

Multiplicity of primary malignancies itself does not seem to indicate a poor prognosis. The early detection of additional primary malignancies will enable proper management with curative intent.

 

 

Synchronous Gastric Cancer

 Video Endoscopic Sequence 4 of 4.

Endoscopy of adenocarcinoma of the antrum second neoplasia.

 

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